Yamazaki N, Shinohara Y, Shima A, Yamanaka Y, Terada H
Faculty of Pharmaceutical Sciences, University of Tokushima, Japan.
Biochim Biophys Acta. 1996 Jun 7;1307(2):157-61. doi: 10.1016/0167-4781(96)00069-3.
With a cDNA probe encoding rat muscle type carnitine palmitoyltransferase I (CPTI), we isolated cDNA and genomic clones encoding the human homologue and deduced the primary structure of human muscle type CPTI. By Northern analysis, we confirmed the dominant expression of this isoform in heart and skeletal muscle.
利用编码大鼠肌肉型肉碱棕榈酰转移酶I(CPTI)的cDNA探针,我们分离出了编码人同源物的cDNA和基因组克隆,并推导了人肌肉型CPTI的一级结构。通过Northern分析,我们证实了这种同工型在心脏和骨骼肌中的优势表达。