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[肌痛中肌肉组织的磁共振成像——适应证与影像表现]

[MRI of musculature in myalgia--indications and image findings].

作者信息

Beese M S, Winkler G, Maas R, Bücheler E

机构信息

Radiologische Klinik, Universitätsklinik Hamburg Eppendorf.

出版信息

Aktuelle Radiol. 1996 May;6(3):119-29.

PMID:8679735
Abstract

This paper deals with the question of the clinical circumstances in which MRI seems to be promising in patients with myalgia. 241 patients suffering from myalgic symptoms were examined by axial scans of the muscular system with T1w and STIR-sequences. All patients underwent a complete neuromuscular examination, which included an MRI guided muscle-biopsy of 203 patients. The images were retrospectively analysed as to the typical characteristics of differential diagnosis. In cases of idiopathic or bacterial/viral induced myositis, primary vasculitis, and rhabdomyolysis, edematous changes of the muscles could always be found. Abscesses were only found in bacterial myositis. In cases of poly- and dermatomyositis as well as inclusion-body-myositis, MRI showed a uniform distribution pattern with emphasis on the quadriceps muscles. In contrast to other neuromuscular diseases in bacterial induced myositis, focal myositis, and rhabdomyolysis a strong contrast agent enhancement was seen. All patients with myalgic syndromes without any other additional neuropathological findings and 86% of the patients suffering from polymyalgia rheumatica had normal MR-findings. MRI allows a correct exclusion of an inflammatory, tumorous, or rhabdomyolitic cause of a myalgia and leads to pathognomonic findings for these diseases. Diseases belonging to the group of endocrine, toxic, or metabolic myopathies might be normal in MRI. We believe that an indication for MRI is given when muscular pain is associated with additional neuromuscular symptoms, especially if an inflammatory origin of the myalgia is suspected or if a muscle biopsy is planned.

摘要

本文探讨了在肌痛患者中,MRI似乎具有前景的临床情况。对241例有肌痛症状的患者进行了肌肉系统的T1加权和短TI反转恢复(STIR)序列轴位扫描。所有患者均接受了全面的神经肌肉检查,其中203例患者进行了MRI引导下的肌肉活检。对图像进行回顾性分析,以确定鉴别诊断的典型特征。在特发性或细菌/病毒感染性肌炎、原发性血管炎和横纹肌溶解症患者中,总能发现肌肉的水肿改变。脓肿仅在细菌性肌炎中发现。在多发性肌炎、皮肌炎以及包涵体肌炎患者中,MRI显示出以股四头肌为主的均匀分布模式。与细菌性感染性肌炎、局灶性肌炎和横纹肌溶解症等其他神经肌肉疾病不同,可见明显的造影剂强化。所有患有肌痛综合征且无任何其他神经病理学额外发现的患者以及86%的风湿性多肌痛患者MRI检查结果正常。MRI能够正确排除肌痛的炎症性、肿瘤性或横纹肌溶解症病因,并得出这些疾病的特征性表现。属于内分泌、中毒或代谢性肌病组的疾病在MRI上可能表现正常。我们认为,当肌肉疼痛伴有其他神经肌肉症状时,尤其是怀疑肌痛有炎症起源或计划进行肌肉活检时,应考虑进行MRI检查。

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