Tong A D, Rothman A, Atkinson R L, Shiota T, Ricou F, Sahn D J
Division of Pediatric Cardiology, University of California, San Diego Medical Center 92103, USA.
Am J Card Imaging. 1995 Oct;9(4):250-6.
Although the use of balloon dilation for treatment of native and recurrent coarctation of the aorta (coA) has become widespread, the optimal balloon size and postdilation vessel wall changes remain undetermined. Intravascular ultrasound (IVUS) imaging has emerged as a an important adjunct in the treatment and follow-up of patients with coronary artery and peripheral vascular lesions, and has been used for evaluation in a limited number of patients with CoA. We used a combination of balloon dilation/ultrasound imaging catheter in animals with experimentally-induced CoA. We used a combination balloon dilation/ultrasound imaging catheter in animals with experimentally-induced CoA . This technique provided real-time data regarding aortic wall morphology and luminal diameter during balloon angioplasty of the CoA. In humans, we used IVUS to study CoA before and after both transcatheter and surgical therapy. IVUS was more sensitive than angiography in the detection of intimal tears post-balloon dilation and in the evaluation of vessel wall changes and remodelling observed at follow-up after relief of CoA. IVUS may provide valuable information regarding vascular wall changes that predict aneurysm format ion, restenosis, or a successful result after balloon dilation.
尽管使用球囊扩张术治疗原发性和复发性主动脉缩窄（CoA）已广泛应用，但最佳球囊尺寸和扩张后血管壁变化仍未确定。血管内超声（IVUS）成像已成为冠状动脉和外周血管病变患者治疗及随访中的一项重要辅助手段，并已用于对有限数量的CoA患者进行评估。我们在实验性诱导CoA的动物中使用了球囊扩张/超声成像导管组合。我们在实验性诱导CoA的动物中使用了球囊扩张/超声成像导管组合。该技术在CoA球囊血管成形术期间提供了有关主动脉壁形态和管腔直径的实时数据。在人类中，我们使用IVUS研究经导管和手术治疗前后的CoA。IVUS在检测球囊扩张后内膜撕裂以及评估CoA缓解后随访时观察到的血管壁变化和重塑方面比血管造影更敏感。IVUS可能提供有关预测动脉瘤形成、再狭窄或球囊扩张后成功结果的血管壁变化的有价值信息。
