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[运动不足时大鼠前脑结构中毛细血管及毛细血管周围区域的超微结构]

[The ultrastructure of the capillaries and pericapillary area in the formations of the rat forebrain in hypokinesia].

作者信息

Zhvaniia M G, Kakabadze I M

出版信息

Morfologiia. 1994 Jul-Dec;107(7-12):47-53.

PMID:8680572
Abstract

Capillaries and pericapillary tissue were studied in central and lateral nuclei of amygdala, cingulate cortex, hippocampal fields CA1 and CA3 and sensomotor, cortex in rats, exposed to hypokinesia 40, 90 and 120 days lasted. Changes, growing more numerous and variable in proportion with the time of hypokinesia were found. The most essential changes were hypertrophy of glial elements with either decreased or increased functional activity. Alteration of the endotheliocyte structure, pinocytosis, hypertrophy and increase of nuclear and cytoplasmic osmophilia, decrease of the folding were noted. Capillaries with significantly increased folding and narrow or containing unidentified substance lumen were encountered in 120-days hypokinesia. In limbic structures pericapillary glia is represented mostly with astrocytes, in neocortex-also with oligodendrocytes.

摘要

对暴露于40天、90天和120天低动力状态的大鼠杏仁核中央核和外侧核、扣带回皮质、海马CA1区和CA3区以及感觉运动皮质中的毛细血管和毛细血管周围组织进行了研究。发现随着低动力状态持续时间的延长,变化越来越多且各不相同。最主要的变化是神经胶质成分肥大,其功能活性降低或增加。观察到内皮细胞结构改变、胞饮作用、肥大以及核和细胞质嗜碱性增加、褶皱减少。在120天低动力状态下,遇到了褶皱明显增加且管腔狭窄或含有不明物质的毛细血管。在边缘结构中,毛细血管周围的神经胶质主要由星形胶质细胞代表,在新皮质中也有少突胶质细胞。

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