Zhvaniia M G, Kostenko N A
Morfologiia. 1995;108(1):13-6.
Ultrastructure of neurons, synapses and glial elements was studied in the rat motor cortex under exposure to hypokinesia lasting for 40 and 90 days. Changes prevail in all cortical layers in 90-days hypokinesia and in upper ones in 40-days hypokinesia. These are basically reactive or not deep destructive changes. Cell elements and synapses with structural manifestations of low functional activity prevail with the increase of the experimental terms. Astrocyte number including satellite forms significantly grows in 40-days hypokinesia. In 90-days changes occur in all cortical layers with the increase of both astrocyte and oligodendrocyte number.
在持续40天和90天的运动不足状态下,对大鼠运动皮层中的神经元、突触和神经胶质成分的超微结构进行了研究。在90天运动不足状态下,所有皮质层均出现变化;在40天运动不足状态下,上层皮质出现变化。这些变化基本上是反应性的或并非深度破坏性的变化。随着实验时间的延长,具有低功能活性结构表现的细胞成分和突触占主导地位。在40天运动不足状态下,包括卫星状形态在内的星形胶质细胞数量显著增加。在90天运动不足状态下,所有皮质层均发生变化,星形胶质细胞和少突胶质细胞数量均增加。