Lombardi T, Haskell R, Morgan P R, Odell E W
Department of Oral Medicine and Pathology, UMDS Guy's Hospital, London, U.K.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Dec;80(6):677-82. doi: 10.1016/s1079-2104(05)80251-3.
A case is reported of a 31-year-old white man who presented with a solitary melanoma in the maxillary alveolus. The lesion was located between and had displaced the roots of the lateral incisor and canine and was relatively well circumscribed on radiography. No mucosal origin or potential primary lesion was found, and a marginal excision resulted in the patient remaining free from disease after 7 years of follow-up. Metastasis of melanoma to the jaws is rare even in disseminated disease, and this solitary lesion is unusual. Although metastasis from a regressed primary tumor cannot be excluded, some of the features raise the possibility that this melanoma may have arisen as a primary tumor within bone.
报告了一例31岁白人男性病例，该患者上颌牙槽出现孤立性黑色素瘤。病变位于侧切牙和尖牙牙根之间并使其移位，X线片显示边界相对清晰。未发现黏膜起源或潜在原发灶，边缘切除术后患者经过7年随访无疾病复发。黑色素瘤转移至颌骨即使在播散性疾病中也很罕见，而这种孤立性病变并不常见。虽然不能排除来自消退原发肿瘤的转移，但一些特征提示该黑色素瘤有可能是在骨内原发形成的。
