Chaoui R, Heling K S, Taddei F, Bollmann R
Abteilung Pränatale Diagnostik und Therapie, Humboldt-Universität Berlin.
Z Geburtshilfe Neonatol. 1996 Jan-Feb;200(1):13-20.
Pulsed Doppler velocimetry of both fetal atrioventricular valves derived in the four-chamber-view were performed in 94 uncomplicated pregnancies between the 20th and the 40th week of gestation. The maximal velocities in early (E-peak) and late diastole (A-Peak) as well as the E/A Ratio were calculated for both tricuspid (TV) and mitral valves (MV). Normal ranges for the six measured parameters were constructed and correlated with gestational age. In the second half of pregnancy an increase of the E-wave for both valves was found (TV r = 0,59; MV r = 0,48) with higher values through the TV compared with the MV. In comparison the A-velocities showed a flat increase during the observation time (TV r = 0,32, MV r = 0,24). The E/A Ratio for both valves which is < 1 in the fetus showed an increase throughout pregnancy, mainly due to the increase of the E-wave in the observed period of time. These intracardiac Doppler flow measurements enable an insight into the physiology of fetal circulation. They give a basis for the analysis of blood flow under pathological conditions, like in congenital heart defects or in intrauterine growth retardation.
对94例孕20至40周的正常妊娠孕妇,在四腔心切面测量胎儿房室瓣的脉冲多普勒流速。计算三尖瓣(TV)和二尖瓣(MV)舒张早期(E峰)、舒张晚期(A峰)的最大流速以及E/A比值。构建六个测量参数的正常范围,并与孕周进行相关性分析。妊娠后半期,发现两个瓣膜的E波均升高(TV r = 0.59;MV r = 0.48),且TV的值高于MV。相比之下,A流速在观察期呈平缓升高(TV r = 0.32,MV r = 0.24)。胎儿的两个瓣膜E/A比值均<1,在整个孕期该比值升高,主要是由于观察期内E波升高。这些心内多普勒血流测量有助于深入了解胎儿循环生理。它们为分析先天性心脏病或宫内生长迟缓等病理状况下的血流提供了依据。