Gualdi G F, Di Biasi C, D'Agostino A, Trasimeni G, Melone A
Istituto di I Clinica Medica, Università degli Studi di Roma.
Clin Ter. 1995 Dec;146(12):843-56.
Fifty-eight patients with AIDS disease were studied with MR imaging in the aim of detecting the grade of brain involvement. The examinations were performed with a 1.5 Tesla magnet. Thirty-seven showed white matter lesion (63.5%), twenty-five patients showed cerebral atrophy (43%), in eight patients the MR appearance was consistent with toxoplasmosis infection (13.5%), two patients showed a linfoma (3.4%) and two patients micrococcosis (3.4%). Seventeen out of the thirty-seven patients with white matter disease showed focal well circumscribed lesion (46%), while twenty showed diffuse involvement. Between the twenty-five patients with cerebral atrophy, twelve showed a prevalence of the cortical involvement and eight a subcortical atrophy. In five patients a concomitant, cortical and subcortical atrophy was found. Between the eight patients with neurotoxolesion and two of them a widespread encephalitis picture. The MR appearance of the two limphomas was that of periventricular, space occupying, masses. In two patients with micrococcis a nodular aspect of leptomeningeal lesions was found.
对58例艾滋病患者进行了磁共振成像(MR)研究,目的是检测脑部受累程度。检查使用1.5特斯拉磁体进行。37例显示白质病变(63.5%),25例患者显示脑萎缩(43%),8例患者的MR表现符合弓形虫感染(13.5%),2例患者显示淋巴瘤(3.4%),2例患者显示微小隐球菌病(3.4%)。37例白质疾病患者中有17例显示局灶性边界清晰的病变(46%),而20例显示弥漫性受累。在25例脑萎缩患者中,12例以皮质受累为主,8例以皮质下萎缩为主。5例患者同时存在皮质和皮质下萎缩。在8例有神经毒素病变的患者中,2例表现为广泛的脑炎图像。2例淋巴瘤的MR表现为脑室周围占位性肿块。2例微小隐球菌病患者发现软脑膜病变呈结节状。