Alós J I, Barros C, Gómez-Garcés J L
Servicio de Microbiología, Hospital de Móstoles, Madrid, Spain.
Eur J Clin Microbiol Infect Dis. 1995 Dec;14(12):1085-8. doi: 10.1007/BF01590944.
A 33-year-old, active intravenous drug-abusing male infected with the human immunodeficiency virus developed endocarditis due to Arcanobacterium haemolyticum. Empirical treatment with ampicillin plus gentamicin failed to achieve a marked clinical improvement. When the results of antibiotic susceptibility were available (ampicillin MIC < or = 0.06 mg/l; ampicillin MBC 2 mg/l; MBC:MIC ratio > 32) therapy was changed to vancomycin plus gentamicin. During the following days progressive clinical and radiological improvement was observed. The patient received antibiotics for 30 days and no relapse occurred during a 14-month follow-up. The literature of endocarditis due to this uncommon bacterium is reviewed here.
一名33岁、有静脉注射毒品史的活跃男性感染了人类免疫缺陷病毒，因溶血隐秘杆菌引发心内膜炎。经验性使用氨苄西林加庆大霉素治疗未能取得显著临床改善。当获得抗生素药敏结果（氨苄西林MIC≤0.06mg/L；氨苄西林MBC 2mg/L；MBC:MIC比值＞32）后，治疗改为万古霉素加庆大霉素。在接下来的几天里，观察到临床和影像学有逐步改善。患者接受了30天抗生素治疗，在14个月的随访期间未出现复发。本文回顾了关于这种罕见细菌所致心内膜炎的文献。
