Grijseels E W, Deckers J W, Hoes A W, Boersma E, Hartman J A, van der Does E, Simoons M L
Thoraxcentre, Erasmus University Rotterdam, The Netherlands.
Eur Heart J. 1996 Jan;17(1):89-95. doi: 10.1093/oxfordjournals.eurheartj.a014697.
To improve pre-hospital triage of patients with suspected acute cardiac disease.
Prospective study. SUBJECTS. Patients with symptoms suggestive of acute cardiac pathology, who were seen by a general practitioner, for whom acute admission into hospital was requested, and in whom a pre-hospital electrocardiogram was recorded by the ambulance service.
The study consisted of two phases. In the first phase, a decision rule was developed based on clinical characteristics and electrocardiographic findings in 1005 patients with suspected acute cardiac pathology. In the second phase, the decision rule was prospectively validated. Symptoms were recorded by a standardized questionnaire by the general practitioner and a computerized electrocardiogram was made by the ambulance nurses at the patient's home. Three electrocardiographic outcomes were available: 'normal electrocardiogram', 'possible myocardial infarction' or 'extensive myocardial infarction'. By use of the predictive model, the general practitioner could decide if hospitalization was necessary or not.
Identification of patients at low (stable angina, atypical chest pain, other pathology) and high (myocardial infarction, unstable angina) probability of acute cardiac pathology.
Among 977 patients with a complete pre-hospital evaluation in the validation phase of the study, the decision rule recommended 'no hospitalization' in 227 patients (23%). The general practitioner followed this advice in 44% of these patients. Although seven of them developed a non-Q wave myocardial infarction, no complications occurred in patients not admitted. In addition, the general practitioner did not hospitalize 19 (2%) of 750 patients for whom the decision rule recommended admission. Pre-hospital triage by the general practitioner resulted in a 12% (118 of 977 patients) reduction of the number of patients admitted to the Coronary Care Units.
Pre-hospital triage by the general practitioner was facilitated using a standardized questionnaire and pre-hospital electrocardiography, and resulted in a reduction in the number of patients admitted to the Coronary Care Unit, and proved to be safe.
改善疑似急性心脏疾病患者的院前分诊。
前瞻性研究。对象:有急性心脏病变症状、由全科医生诊治、被要求急性入院且由救护服务机构记录了院前心电图的患者。
该研究包括两个阶段。第一阶段,基于1005例疑似急性心脏病变患者的临床特征和心电图表现制定了一个决策规则。第二阶段,对该决策规则进行前瞻性验证。症状由全科医生通过标准化问卷记录,救护护士在患者家中进行电脑化心电图检查。有三种心电图结果:“正常心电图”、“可能心肌梗死”或“广泛心肌梗死”。通过使用预测模型,全科医生可决定是否有必要住院。
识别急性心脏病变低概率(稳定型心绞痛、非典型胸痛、其他病变)和高概率(心肌梗死不稳定型心绞痛)的患者。
在研究验证阶段进行了完整院前评估的977例患者中,决策规则建议227例患者(23%)“无需住院”全科医生在其中44%的患者中遵循了这一建议。尽管其中7例发生了非Q波心肌梗死,但未住院的患者未出现并发症。此外,决策规则建议住院的750例患者中,全科医生未让19例(2%)住院。全科医生进行的院前分诊使冠心病监护病房收治的患者数量减少了12%(977例患者中的118例)。
使用标准化问卷和院前心电图有助于全科医生进行院前分诊,减少了冠心病监护病房收治的患者数量,且证明是安全的。