Franco G, Bisio S
Dipartimento di Scienze biomediche dell'Università di Modena.
G Ital Med Lav. 1994 Jan-Nov;16(1-6):53-6.
The evaluation of health status of workers exposed to a variety of chemicals is usually performed by means of several laboratory indices. Our aim was to assess the influence of some lifestyle characteristics (alcohol intake and cigarettes smoking) on these parameters. 103 subjects occupationally exposed to chemicals and 146 non occupationally exposed subject were studied. A significant increase in gamma-GT, MCV e UDGA was observed among drinkers (> or = 5 g alcohol/day) as compared with non drinkers and among cigarette smokers (> or = 5 cigarettes/day) as compared with non smokers. Statistically cigarette smoking and alcohol intake influenced parameters independently from any occupational exposure to chemicals. Among the explored indices, UDGA only was significantly and positively associated to occupationally exposure to chemicals. Alcohol intake and cigarettes smoking are responsible for a modification of some laboratory parameters in healthy workers. The medical surveillance of workers exposed to chemicals should include a careful evaluation of alcohol intake (when gamma-GT and ADGU are measured) and cigarette smoking (when MCV and ADGU are measured).
对接触多种化学物质的工人的健康状况评估通常通过若干实验室指标来进行。我们的目的是评估某些生活方式特征（饮酒和吸烟）对这些参数的影响。对103名职业性接触化学物质的受试者和146名非职业性接触化学物质的受试者进行了研究。与不饮酒者相比，饮酒者（每天饮酒≥5克）的γ-谷氨酰转移酶、平均红细胞体积和尿脱氧胆酸显著升高；与不吸烟者相比，吸烟者（每天吸烟≥5支）的上述指标也显著升高。从统计学角度来看，吸烟和饮酒对这些参数的影响独立于任何职业性化学物质接触。在所研究的指标中，只有尿脱氧胆酸与职业性化学物质接触呈显著正相关。饮酒和吸烟会导致健康工人的一些实验室参数发生改变。对接触化学物质的工人进行医学监测时，应仔细评估饮酒情况（测量γ-谷氨酰转移酶和尿脱氧胆酸时）和吸烟情况（测量平均红细胞体积和尿脱氧胆酸时）。
