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[对伴有体重减轻的继发性闭经女孩血清中β-内啡肽水平及促性腺激素、催乳素、皮质醇和雌二醇的评估]

[Evaluation of beta-endorphin levels and gonadotropin, prolactin, cortisol and estradiol in serum of girls with secondary amenorrhea associated with weight loss].

作者信息

Meczekalski B, Warenik-Szymankiewicz A

机构信息

Kliniki Endokrynologii Ginekologicznej IGiP AM w Poznaniu.

出版信息

Ginekol Pol. 1995 Oct;66(10):596-9.

PMID:8682346
Abstract

Levels of beta-endorphin, FSH, LH, PRL, cortisol and estradiol in blood serum were measured in 20 girls with weight loss related amenorrhoea. Serum beta-endorphin levels were also measured in a group of 15 young, regularly menstruating healthy girls (control group). Levels of beta-endorphin were significantly lower in examined group than in control one. Serum levels of FSH, LH, estradiol were low. Serum levels of PRL and cortisol were normal. These observations suggest, that beta-endorphin is involved in the pathogenesis of weight loss related amenorrhoea.

摘要

对20名患有与体重减轻相关闭经的女孩测定了血清中β-内啡肽、促卵泡激素(FSH)、促黄体生成素(LH)、催乳素(PRL)、皮质醇和雌二醇的水平。还对15名年轻、月经规律的健康女孩(对照组)测定了血清β-内啡肽水平。研究组的β-内啡肽水平显著低于对照组。血清FSH、LH、雌二醇水平较低。血清PRL和皮质醇水平正常。这些观察结果表明,β-内啡肽参与了与体重减轻相关闭经的发病机制。

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