肝细胞癌患者血清中循环细胞间黏附分子1的水平

Serum levels of circulating intercellular adhesion molecule 1 in hepatocellular carcinoma.

作者信息

Hamazaki K, Gochi A, Shimamura H, Kaihara A, Maruo Y, Doi Y, Orita K, Lygidakis N J

机构信息

First Department of Surgery, Okayama University Medical School.

出版信息

Hepatogastroenterology. 1996 Jan-Feb;43(7):229-34.

PMID:8682469

Abstract

BACKGROUND/AIMS: This is a comparative study of the relationship between.

MATERIAL AND METHODS

Serum levels of circulating intercellular adhesion molecule-1 (cICAM-1) were measured by ELISA assay in four patients with chronic hepatitis (CH), 16 with liver cirrhosis (LC), 38 with hepatocellular carcinoma (HCC), and in nine healthy controls.

RESULTS

No significant difference in cICAM-1 levels was observed between LC and HCC. The cICAM-1 level in HCC did not correlate with tumor markers but correlated well with tumor size. cICAM-1 level in HCC Stage III + IV was significantly higher than that of Stage I, and was higher in HCC with liver metastasis as opposed to HCC without metastasis. Furthermore, the cICAM-1 level of HCC decreased significantly after hepatectomy.

CONCLUSION

These findings showed a close relationship between cICAM-1 and the progress of intrahepatic metastasis of HCC, indicating a possibility for using cICAM-1 as a prognostic marker.

摘要

背景/目的：这是一项关于[具体关系]的对比研究。