Hypoglycemia associated with intra-abdominal leiomyoma and leiomyosarcoma in six dogs.

Intra-abdominal leiomyoma or leiomyosarcoma was diagnosed in 6 dogs that had hypoglycemia (resting blood glucose concentration < 50 mg/dl). Tumors were large (12 to 24 cm) and arose from intra-abdominal structures including the jejunum, pylorus, duodenum, stomach, and liver. Four dogs had a leiomyoma, and 2 dogs had a leiomyosarcoma. In those dogs in which the tumor was successfully removed at surgery, blood glucose concentration returned to the reference range after tumor resection. Four dogs lived for at least 12 months after tumor resection, without redeveloping hypoglycemia.