• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

椎间盘源性下腰痛的传入通路。L2脊神经浸润的评估。

The afferent pathways of discogenic low-back pain. Evaluation of L2 spinal nerve infiltration.

作者信息

Nakamura S I, Takahashi K, Takahashi Y, Yamagata M, Moriya H

机构信息

Department of Orthopaedic Surgery, School of Medicine, Chiba University, Japan.

出版信息

J Bone Joint Surg Br. 1996 Jul;78(4):606-12.

PMID:8682829
Abstract

The afferent pathways of discogenic low-back pain have not been fully investigated. We hypothesised that this pain was transmitted mainly by sympathetic afferent fibres in the L2 nerve root, and in 33 patients we used selective local anaesthesia of this nerve. Low-back pain disappeared or significantly decreased in all patients after the injection. Needle insertion provoked pain which radiated to the low back in 23 patients and the area of skin hypoalgesia produced included the area of pre-existing pain in all but one. None of the nine patients with related sciatica had relief of that component of their symptoms. Our findings show that the main afferent pathways of pain from the lower intervertebral discs are through the L2 spinal nerve root, presumably via sympathetic afferents from the sinuvertebral nerves. Discogenic low-back pain should be regarded as a visceral pain in respect of its neural pathways. Infiltration of the L2 nerve is a useful diagnostic test and also has some therapeutic value.

摘要

椎间盘源性下腰痛的传入通路尚未得到充分研究。我们推测这种疼痛主要由L2神经根中的交感传入纤维传导,在33例患者中,我们对该神经进行了选择性局部麻醉。注射后所有患者的下腰痛消失或明显减轻。针刺引发的疼痛放射至23例患者的下背部,除1例患者外,所产生的皮肤感觉减退区域包括先前存在疼痛的区域。9例伴有相关坐骨神经痛的患者中,其症状的该组成部分均未得到缓解。我们的研究结果表明,来自下位椎间盘的主要疼痛传入通路是通过L2脊神经根,可能是通过来自窦椎神经的交感传入纤维。就其神经通路而言,椎间盘源性下腰痛应被视为一种内脏痛。L2神经浸润是一种有用的诊断试验,也具有一定的治疗价值。

相似文献

1
The afferent pathways of discogenic low-back pain. Evaluation of L2 spinal nerve infiltration.椎间盘源性下腰痛的传入通路。L2脊神经浸润的评估。
J Bone Joint Surg Br. 1996 Jul;78(4):606-12.
2
[Relevance of nerve blocks in treating and diagnosing low back pain--is the quality decisive?].[神经阻滞在治疗和诊断腰背痛中的相关性——质量起决定性作用吗?]
Schmerz. 2001 Dec;15(6):474-83. doi: 10.1007/s004820100035.
3
The pathogenesis and clinical significance of a high-intensity zone (HIZ) of lumbar intervertebral disc on MR imaging in the patient with discogenic low back pain.腰椎间盘源性下腰痛患者磁共振成像中椎间盘高强度区(HIZ)的发病机制及临床意义
Eur Spine J. 2006 May;15(5):583-7. doi: 10.1007/s00586-005-0892-8. Epub 2005 Jul 27.
4
Evaluation of the L2 spinal nerve root infiltration as a diagnostic tool for discogenic low back pain.评估L2脊神经根浸润作为椎间盘源性下腰痛诊断工具的价值。
Pain Physician. 2005 Jan;8(1):55-9.
5
Sympathetic afferent units from lumbar intervertebral discs.来自腰椎间盘的交感传入神经单元。
J Bone Joint Surg Br. 2006 Apr;88(4):554-7. doi: 10.1302/0301-620X.88B4.17194.
6
Anterior herniation of lumbar disc induces persistent visceral pain: discogenic visceral pain: discogenic visceral pain.腰椎间盘前突导致持续性内脏疼痛:椎间盘源性内脏痛:椎间盘源性内脏痛。
Chin Med J (Engl). 2013;126(24):4691-5.
7
Effectiveness of L2 spinal nerve infiltration for selective discogenic low back pain patients.L2 脊神经浸润对选择性椎间盘源性下腰痛患者的疗效。
J Orthop Sci. 2010 Nov;15(6):731-6. doi: 10.1007/s00776-010-1538-1. Epub 2010 Nov 30.
8
Effect of the L2 ramus communicans on the nociceptive pathway in lumbar intervertebral discs in rats.大鼠L2交通支对腰椎间盘伤害感受通路的影响。
Eur J Pain. 2008 Aug;12(6):798-803. doi: 10.1016/j.ejpain.2007.12.001. Epub 2008 Feb 1.
9
Origin of nerves supplying the posterior portion of lumbar intervertebral discs in rats.大鼠腰椎间盘后部神经的来源
Spine (Phila Pa 1976). 1996 Apr 15;21(8):917-24. doi: 10.1097/00007632-199604150-00003.
10
[Anatomical background of low back pain: variability and degeneration of the lumbar spinal canal and intervertebral disc].[腰痛的解剖学背景:腰椎管和椎间盘的变异性与退变]
Schmerz. 2001 Dec;15(6):418-24. doi: 10.1007/s004820100026.

引用本文的文献

1
Updates on Pathophysiology of Discogenic Back Pain.椎间盘源性下腰痛的病理生理学进展
J Clin Med. 2023 Nov 2;12(21):6907. doi: 10.3390/jcm12216907.
2
Engineering a multicompartment in vitro model for dorsal root ganglia phenotypic assessment.用于背根神经节表型评估的多室体外工程模型。
J Biomed Mater Res B Appl Biomater. 2023 Nov;111(11):1903-1920. doi: 10.1002/jbm.b.35294. Epub 2023 Jun 16.
3
Sensory innervation of the lumbar 5/6 intervertebral disk in mice.小鼠腰5/6椎间盘的感觉神经支配
Front Neurol. 2023 Apr 3;14:1084209. doi: 10.3389/fneur.2023.1084209. eCollection 2023.
4
Best Practices for Dorsal Root Ganglion Stimulation for Chronic Pain: Guidelines from the American Society of Pain and Neuroscience.慢性疼痛背根神经节刺激的最佳实践:美国疼痛与神经科学学会指南
J Pain Res. 2023 Mar 14;16:839-879. doi: 10.2147/JPR.S364370. eCollection 2023.
5
Discogenic Low Back Pain: Anatomy, Pathophysiology and Treatments of Intervertebral Disc Degeneration.椎间盘源性下腰痛:椎间盘退变的解剖学、病理生理学和治疗方法。
Int J Mol Sci. 2022 Dec 22;24(1):208. doi: 10.3390/ijms24010208.
6
Netrin-1 mediates nerve innervation and angiogenesis leading to discogenic pain.Netrin-1介导神经支配和血管生成,导致椎间盘源性疼痛。
J Orthop Translat. 2022 Dec 23;39:21-33. doi: 10.1016/j.jot.2022.11.006. eCollection 2023 Mar.
7
Sinuvertebral nerve block treats discogenic low back pain: a retrospective cohort study.窦椎神经阻滞治疗椎间盘源性下腰痛:一项回顾性队列研究。
Ann Transl Med. 2022 Nov;10(22):1219. doi: 10.21037/atm-22-5297.
8
Comparison of the Clinical Effectiveness Between Infrared Thermography and Electrophysiology Tests in Spinal Intradural Extramedullary Schwannoma.红外热成像与电生理检查在脊髓髓外硬膜下神经鞘瘤临床疗效的比较
Korean J Neurotrauma. 2022 Sep 1;18(2):306-313. doi: 10.13004/kjnt.2022.18.e38. eCollection 2022 Oct.
9
Anterolateral intervertebral disc herniation presenting as visceral pain in a patient with renal keratinising desquamative squamous metaplasia.前外侧椎间盘突出症表现为肾角化性鳞状化生患者的内脏痛。
BMJ Case Rep. 2021 Apr 23;14(4):e240124. doi: 10.1136/bcr-2020-240124.
10
Sensory nerve ingrowth, cytokines, and instability of discogenic low back pain: A review.感觉神经长入、细胞因子与椎间盘源性下腰痛的不稳定性:综述
Spine Surg Relat Res. 2018 Jan 27;2(1):11-17. doi: 10.22603/ssrr.2016-0018. eCollection 2018.