Ino T, Ohkubo M, Akimoto K, Nishimoto K, Yabuta K, Kawasaki S, Watanabe M, Hosoda Y
Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan.
Jpn Circ J. 1996 Feb;60(2):102-7. doi: 10.1253/jcj.60.102.
The effects of stretch and immediate recoil after balloon angioplasty were evaluated in 21 patients with coarctation of the aorta who underwent balloon coarctation angioplasty. A total of 28 procedures were performed in these patients, who ranged in age from 1 month to 17 years with a mean of 4.3 years. The systolic pressure gradient and coarcted diameter changed significantly from 42 +/- 22 to 14 +/- 9 mmHg (P < 0.0001) and from 4.0 +/- 1.7 to 6.1 +/- 2.0 mm (P < 0.001), respectively. Immediate recoil was responsible for the loss of 33% of the potentially achievable coarcted dimension. Recoil was determined mainly by the degree of arterial stretch. Gain increased exponentially with an increase in stretch. There was a narrow range of % stretch (60-80%) within which an effective diameter gain could be obtained. Both gain and stretch were the best predictors for late restenosis: patients with a larger immediate gain and stretch developed more restenosis. These results suggest that the stretch-recoil-gain relationship may be clinically important for evaluating the best predictor of late restenosis after balloon coarctation angioplasty.
对21例接受球囊缩窄血管成形术治疗的主动脉缩窄患者,评估了球囊血管成形术后的拉伸及即刻回弹效应。这些患者共接受了28次手术,年龄从1个月至17岁不等,平均年龄为4.3岁。收缩压梯度和缩窄直径分别从42±22 mmHg显著降至14±9 mmHg(P<0.0001),以及从4.0±1.7 mm显著增至6.1±2.0 mm(P<0.001)。即刻回弹导致潜在可实现的缩窄尺寸损失33%。回弹主要由动脉拉伸程度决定。增益随拉伸增加呈指数增长。存在一个较窄的拉伸百分比范围(60-80%),在此范围内可获得有效的直径增加。增益和拉伸都是晚期再狭窄的最佳预测指标:即刻增益和拉伸较大的患者发生更多再狭窄。这些结果表明,拉伸-回弹-增益关系对于评估球囊缩窄血管成形术后晚期再狭窄的最佳预测指标可能具有临床重要性。