Cooper R S, Ritter S B, Golinko R J
Circulation. 1984 Nov;70(5):903-7. doi: 10.1161/01.cir.70.5.903.
Balloon dilatation angioplasty was successfully performed in five patients (ages 18 months to 17 years) with discrete aortic coarctation. The catheter size was No. 8F or 9F. Selection of balloon diameter was based on angiographic measurements of the aorta determined proximal and distal to the coarctation site. A 10 sec inflation-deflation cycle at 6 to 8 atmospheres (90 to 120 psi) was performed. The systolic pressure gradients across the coarctation before balloon dilatation angioplasty ranged from 35 to 70 mm Hg. Systolic pressure gradients after balloon dilatation angioplasty ranged from 0 to 10 mm Hg. All patients had normalized blood pressure immediately. Abnormal pulsed Doppler echocardiograms were observed in all patients before balloon dilatation angioplasty; four patients had normal echocardiograms after balloon dilatation angioplasty. No serious intraprocedural complications occurred. One patient required femoral artery thrombectomy 36 hr after balloon dilatation angioplasty. One to 6 months after balloon dilatation angioplasty no patients have evidence of restenosis of coarctation. Early results suggest that balloon dilatation angioplasty may offer a safe and effective nonsurgical alternative for the treatment of discrete coarctation in older infants and children. Long-term follow-up for the incidence of restenosis and formation of aneurysms will ultimately determine the efficacy and safety of this procedure.
对5例(年龄18个月至17岁)患有局限性主动脉缩窄的患者成功实施了球囊扩张血管成形术。导管尺寸为8F或9F。球囊直径的选择基于对缩窄部位近端和远端主动脉的血管造影测量。在6至8个大气压(90至120磅力/平方英寸)下进行10秒的充放气循环。球囊扩张血管成形术前缩窄部位的收缩压梯度为35至70毫米汞柱。球囊扩张血管成形术后收缩压梯度为0至10毫米汞柱。所有患者的血压立即恢复正常。在球囊扩张血管成形术前,所有患者的脉冲多普勒超声心动图均异常;球囊扩张血管成形术后,4例患者的超声心动图正常。术中未发生严重并发症。1例患者在球囊扩张血管成形术后36小时需要进行股动脉血栓切除术。球囊扩张血管成形术后1至6个月,无患者有缩窄再狭窄的证据。早期结果表明,球囊扩张血管成形术可能为大龄婴儿和儿童局限性缩窄的治疗提供一种安全有效的非手术替代方法。对再狭窄发生率和动脉瘤形成的长期随访将最终确定该手术的疗效和安全性。