Montagna O, Montagna M T, Mele M S, Gramegna M, Laforgia N
Università degli Studi, Bari.
Minerva Pediatr. 1995 Nov;47(11):445-50.
The authors monitored newborns in the Intensive Care Unit and the equipment with culture exams for a period of 6 months in order to evaluate the incidence of microbic infections and eventual clinical manifestations in relation to risk factors and to test the efficacy of the prophylactic and therapeutic measurements adopted. The results evidenced a positivity in the culture exams of 24.4% at the 1st control, 14.3% at the 2nd and no positive results at the 3rd. Only two newborns presented sepsis that was resolved without any consequences. Aimed antimicrobic therapy was begun at the 1st clinical and/or haematochemical sign that could suspect the onset of infection. A careful control of the microbic flora, the use of aimed antibiotic therapy and respect of the hygienic conditions permitted us to obtain an excellent control of the infections the morbidity, mortality, the days of hospitalization and the onset of bacterial resistance.
作者对重症监护病房的新生儿以及相关设备进行了为期6个月的培养检查监测,以评估微生物感染的发生率以及与危险因素相关的最终临床表现,并测试所采取的预防和治疗措施的有效性。结果显示,第一次检查时培养检查的阳性率为24.4%,第二次为14.3%,第三次没有阳性结果。只有两名新生儿出现败血症,但已治愈且无任何后遗症。在出现第一个可能怀疑感染发作的临床和/或血液化学迹象时,即开始针对性抗菌治疗。对微生物菌群的仔细监测、使用针对性抗生素治疗以及遵守卫生条件,使我们能够很好地控制感染、发病率、死亡率、住院天数以及细菌耐药性的发生。