Brans J W, Aramideh M, Schlingemann R O, Oen V M, Speelman J D, Ongerboer de Visser B W
Academisch Medisch Centrum, Afd. Neurologie, Amsterdam.
Ned Tijdschr Geneeskd. 1996 May 11;140(19):1031-3.
Two patients, men aged 82 and 53 years, with weakness of the facial muscles after surgery in the posterior fossa had keratitis caused by the inability to blink and to close the eye. Botulinum toxin type A was injected into the levator palpebrae superioris muscle under electromyographic control. A selective, reversible paralysis of this muscle was induced without weakness of the anatomically related rectus superior muscle. This botulinum toxin-induced protective ptosis appeared to be effective and safe in the treatment and prevention of keratitis in patients with a temporary weakness of the facial muscles.
两名患者，分别为82岁和53岁男性，在后颅窝手术后出现面部肌肉无力，因无法眨眼和闭眼而导致角膜炎。在肌电图控制下，将A型肉毒杆菌毒素注射到上睑提肌中。诱导该肌肉出现选择性、可逆性麻痹，而与之解剖相关的上直肌无无力表现。这种肉毒杆菌毒素诱导的保护性上睑下垂在治疗和预防面部肌肉暂时无力患者的角膜炎方面似乎是有效且安全的。
