De Palma G D, Di Matteo E, Monaco A, Abbruzzese P, Belardo A, Catanzano C
Cattedra di Chirurgia dell'Apparato Digerente, Università degli Studi di Napoli Federico II, Napoli.
Minerva Chir. 1996 Mar;51(3):87-91.
Between November 1986 and December 1993, 94 patients underwent endoscopic laser therapy for inoperable colo-rectal cancers. According to the main clinical symptoms, tumors were divided into obstructing and bleeding; A Nd-YAG non contact laser was used at power setting of 70 to 100 watt. In 28 cases laser therapy was carried out after electrorection of the tumor and in 22 cases after dilation; in 41 cases it was associated with radiation therapy. In 90% of bleeding tumors and in 70% of obstructing tumors we achieved a good result in the short term. In 50% of bleeding tumors and in 65% of obstructing tumors the symptoms recurred after an interval of 8.2 and 6.1 weeks. The main survival period was 11.2 months for bleeding tumors and 7.4 months for obstructing tumors. Two patients with a small rectal cancer are free to neoplasia at 19 and 26 months after laser therapy.
1986年11月至1993年12月期间，94例无法手术的结直肠癌患者接受了内镜激光治疗。根据主要临床症状，肿瘤分为梗阻型和出血型；使用Nd-YAG非接触式激光，功率设置为70至100瓦。28例患者在肿瘤电切术后进行激光治疗，22例在扩张术后进行；41例与放射治疗联合进行。90%的出血型肿瘤和70%的梗阻型肿瘤在短期内取得了良好效果。50%的出血型肿瘤和65%的梗阻型肿瘤在间隔8.2周和6.1周后症状复发。出血型肿瘤的主要生存期为11.2个月，梗阻型肿瘤为7.4个月。两名患有小直肠癌的患者在激光治疗后19个月和26个月时无肿瘤复发。
