[Pertussis. Critical revision of its physiopathology. Implications].

The re-examination of Bordetella pathogenic power and of the mechanisms which regulate relations between these bacteria and men make us conclude that in pertussis and with intramuscular vaccines an antihistaminic "coverage" is needed and antipertussis vaccinations is to be made by natural way. Via aerosol, minor intrinsic toxicity of acellular vaccines will be determinant.