Poczopko P, Uliasz M
Acta Physiol Pol. 1977 Jan-Feb;28(1):51-60.
Hormonal regulation of thermogenesis in goslings. The effects of blockade with thiouracil and propranolol. Acta Physiol. Pol. 1977, 28 (1): 51-60. The experiments were carried out on 90 male goslings of White Italian breed. In goslings 5 to 7 and 18 to 21-day-old thiouracil (6 mg/100 g i.p., for 3 consecutive days) diminished the cold-induced increase in the metabolic rate. At the end of 1.5 h exposure to 5 degrees C a small but statistically significant drop of body temperature in the thiouracil-treated goslings was noted. Propranolol treatment (2 mg/kg s.c.) had no clear effect neither on body temperature of cold exposed goslings nor on the cold-induced increase in the metabolic rate. The drug caused a significant decrease in the plasma free fatty acid (FFA) levels only in the goslings kept at thermoneutrality. In those exposed to 5 degrees C the plasma FFA levels rose both in the control and propranolol-treated goslings. This suggests that the cold-induced lipolysis in the goslings may be accomplished without mediation of noradrenaline.
雏鹅产热的激素调节。硫脲和普萘洛尔阻断作用的影响。《波兰生理学杂志》1977年，28(1):51 - 60。实验选用90只白色意大利品种雄性雏鹅。对于5至7日龄和18至21日龄的雏鹅，硫脲（腹腔注射6毫克/100克，连续3天）减少了寒冷诱导的代谢率增加。在暴露于5摄氏度1.5小时结束时，发现硫脲处理的雏鹅体温有小幅但具有统计学意义的下降。普萘洛尔处理（皮下注射2毫克/千克）对寒冷暴露雏鹅的体温以及寒冷诱导的代谢率增加均无明显影响。该药物仅在处于热中性状态的雏鹅中导致血浆游离脂肪酸（FFA）水平显著降低。在暴露于5摄氏度的雏鹅中，对照组和普萘洛尔处理组的雏鹅血浆FFA水平均升高。这表明雏鹅寒冷诱导的脂肪分解可能无需去甲肾上腺素介导即可完成。
