Uliasz-Poniewierska M
Acta Physiol Pol. 1982 Jul-Aug;33(4):327-36.
The reported experiments were carried out on 147 male Wistar rats weighing 325 to 400 g kept on normal diet or fasted for 24 hours. These rats were treated with adrenaline, noradrenaline or propranolol (400 micrograms/kg subcutaneously) or were exposed to a temperature of 15 degrees C for 2 hours before and after propranolol injection (400 micrograms/kg). The metabolic rate (MR), respiratory quotient (RQ) and the levels of free fatty acids (FFA), glucose (G) and urea (U) in the plasma were determined. The conclusion was drawn that none of the determined indices alone is a good indicator of changes in the catabolism of lipids, carbohydrates or proteins. However, in the light of the results, simultaneous determination of all parameters, MR including, can provide an indirect information on the role of different substrates in cold thermogenesis.
所报道的实验是在147只体重325至400克的雄性Wistar大鼠身上进行的，这些大鼠要么正常饮食，要么禁食24小时。给这些大鼠皮下注射肾上腺素、去甲肾上腺素或普萘洛尔（400微克/千克），或者在注射普萘洛尔（400微克/千克）前后将其置于15摄氏度的环境中2小时。测定了代谢率（MR）、呼吸商（RQ）以及血浆中游离脂肪酸（FFA）、葡萄糖（G）和尿素（U）的水平。得出的结论是，所测定的指标单独一项都不是脂质、碳水化合物或蛋白质分解代谢变化的良好指标。然而，根据结果，同时测定所有参数，包括代谢率，可以间接提供不同底物在冷产热中作用的信息。
