Moore R G, Partin A W, Kavoussi L R
Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland, USA.
Semin Surg Oncol. 1996 Mar-Apr;12(2):139-44. doi: 10.1002/(SICI)1098-2388(199603/04)12:2<139::AID-SSU9>3.0.CO;2-A.
Laparoscopic surgical techniques were originally applied to the staging of prostate cancer in the form of laparoscopic pelvic lymph node dissection. The efficiency of laparoscopic pelvic lymph node dissection has proven to be comparable to open lymphadenectomy in tissue yield and also shows a considerable decrease in postoperative morbidity. Subsequently, laparoscopy has been used as an adjuvant to perineal prostatectomy for preliminary dissection of the seminal vesicles. Laparoscopic radical prostatectomy has been performed but the long-term efficacy of this treatment is unknown at this point. Future clinical applications of laparoscopic surgical techniques in the diagnosis and treatment of prostate cancer include harvesting of primary and metastatic prostatic tissue for adjuvant gene therapies for prostate cancer.
腹腔镜手术技术最初以腹腔镜盆腔淋巴结清扫术的形式应用于前列腺癌的分期。腹腔镜盆腔淋巴结清扫术在组织获取量方面的效率已被证明与开放性淋巴结切除术相当，并且术后发病率也显著降低。随后，腹腔镜检查已被用作会阴前列腺切除术的辅助手段，用于精囊的初步清扫。已经开展了腹腔镜根治性前列腺切除术，但目前这种治疗方法的长期疗效尚不清楚。腹腔镜手术技术在前列腺癌诊断和治疗中的未来临床应用包括获取原发性和转移性前列腺组织，用于前列腺癌的辅助基因治疗。
