Bernhard P, Obel N
Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark.
Scand J Infect Dis. 1995;27(6):623-5. doi: 10.3109/00365549509047078.
We describe a 28-year-old HIV-infected woman with AIDS, defined by cerebral toxoplasmosis and a CD4-count of less than 10 x 10(6) cells/I, who, after several eruptions of genital herpes and typical dermatomal herpes zoster, all successfully treated with acyclovir, developed chronic cutaneous ulcerating lesions on a finger and on the tibia. The lesions were found to contain varicella zoster virus antigen but repeated treatment courses with acyclovir were unsuccessful. After a course of intravenous foscarnet the lesions resolved. They recurred after discontinuation of foscarnet but finally responded to a second course of treatment.
我们描述了一名28岁的感染HIV的女性，患有艾滋病，其诊断依据为脑弓形虫病和CD4细胞计数低于10×10⁶个/升。该患者在多次发生生殖器疱疹和典型的皮节带状疱疹且均用阿昔洛韦成功治疗后，手指和胫骨出现慢性皮肤溃疡性病变。发现病变部位含有水痘带状疱疹病毒抗原，但多次使用阿昔洛韦治疗均未成功。静脉注射膦甲酸钠一个疗程后病变消退。膦甲酸钠停用后病变复发，但最终对第二个疗程的治疗有反应。
