Rivera-Diaz J, Moosvi A R
Department of Medicine, Jersey Medical Center, Neptune, NJ.
South Med J. 1996 Jul;89(7):711-3. doi: 10.1097/00007611-199607000-00012.
We report the case of a patient with recurrent admissions for congestive heart failure who was subsequently diagnosed with apical hypertrophic cardiomyopathy. The major physiologic characteristic of patients with apical hypertrophic cardiomyopathy is diastolic dysfunction due to abnormal stiffness of the left ventricle during diastole, with resultant impaired ventricular filling. In these patients, as in all patients with hypertrophic cardiomyopathy, the main pathology is inadequate relaxation of the ventricle; therefore, a regimen of diuretics and inotropic agents can actually worsen the clinical picture. We emphasize the need to consider hypertrophic cardiomyopathy in evaluating cases of congestive heart failure.
我们报告了一例因充血性心力衰竭反复入院的患者,该患者随后被诊断为肥厚型心肌病。肥厚型心肌病患者的主要生理特征是舒张期左心室僵硬度异常导致舒张功能障碍,进而心室充盈受损。在这些患者中,与所有肥厚型心肌病患者一样,主要病理改变是心室舒张不足;因此,利尿剂和正性肌力药物治疗方案实际上可能会使临床情况恶化。我们强调在评估充血性心力衰竭病例时需要考虑肥厚型心肌病。