[Treatment of uncomplicated gonorrhea in adults. New guidelines from the working group against gonorrhea].

Only 229 cases of gonococcal infection were recorded in Norway in 1994 (population 4.3 million), as against more than 14,000 cases two decades before. Up to now aminopenicillins with probenecid have been the standard treatment. In 1994, 29% of the reported cases of gonococcal infection were caused by a betalactamase-producing strain. We now recommend treating uncomplicated gonococcal infections with a single oral dose of ciprofloxacin 500 mg, or ofloxacin 400 mg. Pregnant or lactating women should receive intramuscular injections of cefotaxim 500 mg, or spectinomycin 2 g. Test-of-cure is essential. Its main purpose is to discover resistant strains and reinfections. Thorough contact tracing is more important than ever. Culture verification, susceptibility testing and test-of-cure in all cases will influence the continuous reevaluation of these guidelines.