Daugaard H, Kristensen J K, Olgaard K
Nefrologisk afdeling P, Rigshospitalet, København.
Ugeskr Laeger. 1996 Apr 29;158(18):2521-5.
Renal stone disease is a common disorder causing much discomfort and high rates of sick-leave. Surgical treatment has improved dramatically with extracorporeal shock wave lithotripsy, but the recurrence rate is high, and it would be desirable to be able to offer the patients effective steps in prevention of further stone formation. The biochemical abnormalities associated with stone formation are complex and not fully elucidated. It should, however, be possible to reduce the recurrence rate with a relatively simple programme for investigation of the patients. The pathogenesis of renal stones is, therefore, reviewed with reference to a plan for the practical approach to the prevention and management of nephrolithiasis, that has recently been recommended by The National Kidney Foundation, USA.
肾结石病是一种常见疾病，会引起诸多不适并导致高病假率。随着体外冲击波碎石术的出现，手术治疗有了显著改善，但复发率很高，若能为患者提供预防结石进一步形成的有效措施将是理想的。与结石形成相关的生化异常情况复杂且尚未完全阐明。然而，通过一个相对简单的患者检查方案，应该有可能降低复发率。因此，参考美国国家肾脏基金会最近推荐的预防和治疗肾结石的实用方法计划，对肾结石的发病机制进行了综述。
