Stejfa M
I. interní klinika FN U sv. Anny LF MU, Brno.
Vnitr Lek. 1996 Feb;42(2):71-7.
The submitted review deals with contemporary possibilities of antianginal treatment. After a brief account of pathophysiological and morphological data in different types of cardiac ischaemia and angina pectoris the author submits algorithms which should be the basis for therapeutic decisions. It is a question of proper timing of invasive examinations leading to revascularization operations in relation to medicamentous treatment. The latter is supplementary treatment before or after revascularization, or is the main approach in case of minimal complaints, in case of contraindicated invasive treatment or in case of an inoperable finding. The author discusses the action, indications, contraindications, undesirable effects, and average dosage of nitrates, beta-blockers, calcium channel inhibitors and antithrombotics. The author mentions also the use of angiotensin converting enzyme inhibitors. View on treatment will change with advancing knowledge.
所提交的综述探讨了抗心绞痛治疗的当代可能性。在简要阐述不同类型心脏缺血和心绞痛的病理生理及形态学数据后，作者提出了应作为治疗决策基础的算法。这涉及到与药物治疗相关的导致血运重建手术的侵入性检查的恰当时间安排。药物治疗是血运重建之前或之后的辅助治疗，或者在症状轻微、侵入性治疗禁忌或存在无法手术的情况时作为主要治疗方法。作者讨论了硝酸盐类、β受体阻滞剂、钙通道抑制剂和抗血栓药物的作用、适应证、禁忌证、不良反应及平均剂量。作者还提到了血管紧张素转换酶抑制剂的使用。随着知识的不断进步，治疗观点将会发生变化。
