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[长期饮用含抗坏血酸的水对Wistar大鼠石棉诱导的胸膜致癌作用的修饰效应]

[The modifying effect of long-term administration of ascorbic acid with drinking water on asbestos-induced pleural carcinogenesis in Wistar rats].

作者信息

Stadnikova N M, Vasil'eva L A, Shelepov V P, Pylev L N

出版信息

Vopr Onkol. 1996;42(1):85-8.

PMID:8686252
Abstract

Ascorbic acid administered with drinking water, in a concentration of 2.5%, together with sucrose (1%) was found to significantly inhibit the development of mesothelial and pleural tumors induced in Wistar rats by asbestos treatment. Said agents, however, failed to influence spontaneous carcinogenesis.

摘要

研究发现,以2.5%的浓度与蔗糖(1%)一起添加到饮用水中的抗坏血酸,可显著抑制经石棉处理的Wistar大鼠中诱导产生的间皮瘤和胸膜肿瘤的发展。然而,上述药剂对自发癌变没有影响。

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