Kuzin S N, Mazhul' L A, Snegireva I B, Pliushts O P, Gorbarets I P, Shakhgil'dian I V, Viazov S O
Vopr Virusol. 1996 Mar-Apr;41(2):63-5.
Testing of blood sera of 63 hemophiliacs revealed markers of hepatitides B and C in 97 and 98% cases, respectively. Polymerase chain reaction confirmed the presence of hepatitis C virus (HCV) RNA in 31 (94%) out of 33 sera tested which contained antibodies to HCV. Gene typing of the isolated strains revealed the presence of three types of HCV: 1b (94%), 2a (3%), and 3a (3%). Similar distribution of HCV genotypes was revealed in the blood sera of 39 patients with chronic hepatitis C.
对63名血友病患者的血清检测显示,分别有97%和98%的病例存在乙型和丙型肝炎标志物。聚合酶链反应证实,在33份检测出丙型肝炎病毒(HCV)抗体的血清中,有31份(94%)存在HCV RNA。对分离菌株进行基因分型显示存在三种HCV类型:1b型(94%)、2a型(3%)和3a型(3%)。在39例慢性丙型肝炎患者的血清中也发现了类似的HCV基因型分布。