Luft D
Medizinische Klinik, Abteilung Innere Medizin IV, Tübingen.
Z Arztl Fortbild (Jena). 1996 Apr;90(2):139-43.
Impairment of the autonomic nervous system is frequently detectable in diabetic patients. Symptoms and signs are less often observed but if present may be very important with regard to quality of life, metabolic control, and prognosis. Currently used methods to detect disturbances of the autonomic innervation of the cardiovascular system are easily performed, noninvasive, reliable and reproducible. They are not very time consuming and require only standard technical equipment allowing the quick identification of patients at risk. Damage of the cardiovascular autonomic nerve function may explain apparently disparate complaints and signs, i.e. orthostatic hypotension, painless myocardial ischemia, complications during anesthesia, postprandial hypotension and development of the diabetic food syndrome. The diagnosis of asymptomatic cardiovascular neuropathy should always induce attempts to intensify diabetes treatment because better metabolic control may improve or at least stop deterioration of nerve function.
自主神经系统功能损害在糖尿病患者中常常可以检测到。症状和体征较少见,但一旦出现,对于生活质量、代谢控制和预后可能非常重要。目前用于检测心血管系统自主神经支配紊乱的方法操作简便、无创、可靠且可重复。这些方法不太耗时,仅需标准技术设备,就能快速识别有风险的患者。心血管自主神经功能损害可能解释一些明显不同的症状和体征,如体位性低血压、无痛性心肌缺血、麻醉期间的并发症、餐后低血压以及糖尿病性胃轻瘫综合征的发生。无症状性心血管神经病变的诊断应始终促使人们尝试强化糖尿病治疗,因为更好的代谢控制可能改善或至少阻止神经功能的恶化。