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[手术侧肺通气不足的发病机制]

[The pathogenesis of hypoventilation in the operated lung].

作者信息

Vinnitskiĭ L I, Timerbaev V Kh, Vyzhigina M A, Orlov L Iu, Pletsityĭ A D, Mustafin A Kh, Alekseeva N N

出版信息

Anesteziol Reanimatol. 1996 Jan-Feb(1):6-8.

PMID:8686947
Abstract

The content of immunocompetent cells, activity of lipid peroxidation processes, function of the surfactant system, and levels of prostacyclin and thromboxane were studied in 9 patients with resected lungs in the perioperative period separately for the intact and operated on lung. The function of immunocompetent cells deteriorated in both lungs after surgery. The levels of albumin and thromboxane were increased in the bronchoalveolar washings from the lung operated on reliably more than in those from intact lung, and the surface active characteristics deteriorated. Eight patients developed hypoventilation of the operated on lung in the postoperative period.

摘要

对9例在围手术期行肺切除术的患者,分别研究了其免疫活性细胞含量、脂质过氧化过程活性、表面活性剂系统功能以及前列环素和血栓素水平,观察对象为完整肺叶和手术切除肺叶。术后两侧肺叶的免疫活性细胞功能均出现恶化。手术侧肺叶支气管肺泡灌洗液中的白蛋白和血栓素水平显著高于完整肺叶,且表面活性特征变差。8例患者在术后出现手术侧肺叶通气不足。

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