Vinnitskiĭ L I, Timerbaev V Kh, Vyzhigina M A, Pletsityĭ A D, Orlov L Iu, Mustafin A Kh
Anesteziol Reanimatol. 1996 May-Jun(3):18-21.
Twenty-seven patients operated on the lungs and heart (aortocoronary bypass surgery) were examined. Cellular immunity parameters were studied in venous blood, and the function of immunocompetent cells, status of the surfactant system, and albumin level were assessed in the bronchoalveolar washings off. An impairment of the T-component of cellular immunity (T-suppressors), reduced level of alveolar macrophages and of their phagocytic activity, reduced activity of the surfactant system, and increased albumin content in the bronchoalveolar lavage fluid were revealed in patients with a complicated course of the postoperative period. In patients with a smooth course of the postoperative period these shifts were less expressed. The data indicate the necessity of antibacterial and immunomodulated therapy in such patients before and after surgery.
对27例接受肺部和心脏手术（主动脉冠状动脉搭桥手术）的患者进行了检查。研究了静脉血中的细胞免疫参数，并评估了支气管肺泡灌洗中的免疫活性细胞功能、表面活性剂系统状态和白蛋白水平。结果显示，术后病程复杂的患者存在细胞免疫的T成分（T抑制细胞）受损、肺泡巨噬细胞水平及其吞噬活性降低、表面活性剂系统活性降低以及支气管肺泡灌洗液中白蛋白含量增加的情况。术后病程顺利的患者这些变化表现较轻。数据表明，此类患者在手术前后进行抗菌和免疫调节治疗的必要性。
