肝脏对丙咪嗪的敏感性。
Hepatic sensitivity to imipramine.
作者信息
Weaver G A, Pavlinac D, Davis J S
出版信息
Am J Dig Dis. 1977 Jun;22(6):551-3. doi: 10.1007/BF01072511.
PMID:868834
Abstract
A case of significant hepatic reaction related to imipramine is presented, documented by challenge with imipramine and liver biopsy. The mechanism, while not entirely clear, is presumed to involve hypersensitivity or induction of toxic metabolites.
摘要
本文报告1例与丙咪嗪相关的严重肝脏反应病例，通过丙咪嗪激发试验和肝活检证实。其机制虽不完全清楚，但推测与超敏反应或有毒代谢产物的诱导有关。
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