Kramar N I, Monin V I
Morfologiia. 1995;108(2):39-40.
The present research was aimed at studying the structural trace of the adaptation of the large venous vessels microcirculatory bed to the interrupted action of high hypoxia. To obtain the adaptation 94 Wistar line rats were kept every day for 6 hours in the altitude chamber on the modelled height of 5000 meters for 45 days (control group made 20 animals). Intramural vascular bed was revealed by non-injective methods. The data obtained showed that morphological changes in the anterior and posterior venae cavae microcirculatory bed responding to hypoxia were of compensatory-adaptive nature and displayed in the increase of arteriolo-venulary anastomoses number, growth of all the links capacity and reserve capillaries opening.
本研究旨在探讨大静脉血管微循环床对高海拔间断性缺氧作用的适应性结构变化。为诱导适应性变化，将94只Wistar系大鼠置于海拔5000米模拟高度的氧舱中，每天6小时，持续45天（对照组为20只动物）。采用非注射法显示血管壁内的血管床。结果表明，前后腔静脉微循环床对缺氧的形态学变化具有代偿适应性，表现为动静脉吻合支数量增加、各环节容量增大以及储备毛细血管开放。
