[The adaptation of the microcirculatory bed of the major veins to the intermittent action of high-altitude hypoxia].

The present research was aimed at studying the structural trace of the adaptation of the large venous vessels microcirculatory bed to the interrupted action of high hypoxia. To obtain the adaptation 94 Wistar line rats were kept every day for 6 hours in the altitude chamber on the modelled height of 5000 meters for 45 days (control group made 20 animals). Intramural vascular bed was revealed by non-injective methods. The data obtained showed that morphological changes in the anterior and posterior venae cavae microcirculatory bed responding to hypoxia were of compensatory-adaptive nature and displayed in the increase of arteriolo-venulary anastomoses number, growth of all the links capacity and reserve capillaries opening.