Alcini E, Racioppi M, D'Addessi A, Menchinelli P, Grassetti F, Alcini A
Department of Urology, Universita' Cattolica del S. Cuore, Rome, Italy.
Br J Urol. 1996 May;77(5):688-93.
To evaluate the results obtained with a technique of bladder replacement using a detubularized ileal tract, developed by the authors.
Since 1983, 34 patients have undergone an orthotopic bladder replacement using 35-40 cm of ileum, detubularized and shaped into an 'S' to create a neobladder with a capacity of 100-120 mL. The ureters were anastomosed directly to a 10 cm long intact afferent loop which serves as an anti-reflux mechanism, while a 2 cm long efferent, spatulated loop was used for urethral anastomosis. The mean (SD) follow-up was 32 (33) months.
All the patients were continent during the day, with socially convenient intervals between voids; 3 years after the operation, 10 of 12 patients were continent during the night, with intervals of 2-4 h between voids. The mean post-void residual urine volume was 41 mL and no patient required self-catheterization. There were no derangements of the metabolic status of patients.
This technique was applied knowing that a detubularized intestinal loop has the remarkable ability to increase in capacity over time. Therefore, to maintain the reservoir in good condition over a long period it is important to construct it with an intra-operative capacity of < 120 mL, thus reducing the length of intestine required. This may explain the satisfactory metabolic status of these patients. Moreover, the triplication of the mesentery helps to maintain the sphericity of the neobladder and provides support for the neobladder in the lower pelvis, where it retains the same position as a normal bladder.
评估作者所研发的使用去管化回肠段进行膀胱替代技术的效果。
自1983年起,34例患者接受了原位膀胱替代手术,使用35 - 40厘米的回肠,将其去管化并塑形为“S”形以构建容量为100 - 120毫升的新膀胱。输尿管直接吻合至一段10厘米长完整的传入肠袢,该肠袢起到抗反流机制的作用,而一段2厘米长的传出、呈勺状的肠袢用于尿道吻合。平均(标准差)随访时间为32(33)个月。
所有患者白天均能自主控制排尿,排尿间隔时间方便社交活动;术后3年,12例患者中有10例夜间能自主控制排尿,排尿间隔时间为2 - 4小时。平均排尿后残余尿量为41毫升,无患者需要自我导尿。患者的代谢状态无紊乱。
应用该技术是因为了解去管化肠袢具有随时间显著增加容量的能力。因此,为长期维持储尿囊处于良好状态,术中构建容量<120毫升很重要,这样可减少所需肠道长度。这或许可以解释这些患者令人满意的代谢状态。此外,肠系膜的三重折叠有助于维持新膀胱的球形,并为盆腔下部的新膀胱提供支撑,使其保持与正常膀胱相同的位置。