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肝移植中供体动脉变异:527例连续移植的处理及结果

Donor arterial variations in liver transplantation: management and outcome of 527 consecutive grafts.

作者信息

Soin A S, Friend P J, Rasmussen A, Saxena R, Tokat Y, Alexander G J, Jamieson N V, Calne R Y

机构信息

University of Cambridge Clinical School, Transplant Unit, UK.

出版信息

Br J Surg. 1996 May;83(5):637-41. doi: 10.1002/bjs.1800830515.

DOI:10.1002/bjs.1800830515
PMID:8689206
Abstract

The impact of donor arterial variations and their management was investigated retrospectively in 527 consecutive allografts. Anomalous arteries were found in 161 grafts (30.6 per cent). There was no significant difference in the overall incidence of arterial complications between grafts with normal (3.6 per cent) and abnormal (5.6 per cent) anatomy. However, there was a higher incidence of arterial complications in transplants requiring multiple arterial anastomoses (P = 0.02), or anastomosis of donor vessels to recipient aorta with (P = 0.0003) or without (P = 0.04) an interposition graft for arterial reconstruction. The incidence of biliary complications was similar in grafts with a normal (18.8 per cent) or anomalous (18.0 per cent) arterial supply. Anomalies of hepatic arterial anatomy occur in one-third of all livers and do not compromise graft outcome unless multiple anastomoses or direct anastomosis to the recipient aorta are required for arterial reconstruction.

摘要

对527例连续同种异体移植进行回顾性研究,以探讨供体动脉变异及其处理的影响。在161例移植物(30.6%)中发现了异常动脉。解剖结构正常(3.6%)和异常(5.6%)的移植物之间,动脉并发症的总体发生率无显著差异。然而,需要进行多次动脉吻合的移植手术(P = 0.02),或供体血管与受体主动脉进行吻合(使用(P = 0.0003)或不使用(P = 0.04)插入移植物进行动脉重建)时,动脉并发症的发生率较高。正常(18.8%)或异常(18.0%)动脉供应的移植物中,胆系并发症的发生率相似。肝动脉解剖异常在所有肝脏中占三分之一,除非动脉重建需要多次吻合或直接与受体主动脉吻合,否则不会影响移植物的预后。

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