Multiple keratoses and squamous carcinoma after PUVA treatment of vitiligo.
作者信息
Buckley D A, Rogers S
机构信息
City of Dublin Skin and Cancer Hospital, Ireland.
出版信息
Clin Exp Dermatol. 1996 Jan;21(1):43-5.
PMID:8689768
Abstract
PUVA is known to be carcinogenic when used in the treatment of psoriasis. To date skin cancer has not been demonstrated after PUVA treatment of vitiligo. We report a patient in whom multiple squamous cell carcinomata and keratoses developed in vitiligo areas after a prolonged course of PUVA. PUVA therapy of vitiligo induces repigmentation of affected skin in some patients. An increased frequency of cutaneous neoplasms in depigmented areas is a potential hazard, as in these sites the photoprotective effect of melanin is lacking.
摘要
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