Sais G, Vidaller A, Jucglà A, Peyrí J
Department of Dermatology, Ciutat Sanitària i Universitària de Bellvitge, University of Barcelona, Spain.
Clin Exp Dermatol. 1996 Jan;21(1):65-6. doi: 10.1046/j.1365-2230.1996.d01-162.x.
Cutaneous leucocytoclastic vasculitis is an inflammatory vascular disorder due to deposition of immune complexes in dermal vessels. A direct or indirect role of infectious agents in the pathogenesis of such vasculitis has been postulated. We describe a patient with cervical lymphadenitis due to Mycobacterium tuberculosis infection who developed cutaneous vasculitis. The vasculitis resolved with standard antituberculous therapy. The association between leucocytoclastic vasculitis and tuberculous infection has only rarely been reported. Tuberculous infection may present in a number of different clinical forms depending in part on variations in the number and virulence of the bacilli, route of infection, presence or absence of an internal tuberculous focus, age and specific immunity of the host. Although the association between infection and vasculitis is well known, Mycobacterium tuberculosis as a causative agent of cutaneous leucocytoclastic vasculitis is uncommon.
皮肤白细胞破碎性血管炎是一种由于免疫复合物沉积于真皮血管而引起的炎症性血管疾病。已经推测感染因子在这种血管炎的发病机制中具有直接或间接作用。我们描述了一名因结核分枝杆菌感染导致颈部淋巴结炎并发生皮肤血管炎的患者。该血管炎通过标准抗结核治疗得以缓解。白细胞破碎性血管炎与结核感染之间的关联仅有极少报道。结核感染可能以多种不同临床形式出现，部分取决于杆菌数量和毒力的变化、感染途径、体内是否存在结核病灶、宿主年龄及特异性免疫。尽管感染与血管炎之间的关联众所周知，但结核分枝杆菌作为皮肤白细胞破碎性血管炎的致病因子并不常见。
