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用于大鼠肠道肌电记录的双极电极植入

Bipolar electrode implantation for myoelectrical recordings of rat bowel.

作者信息

Yamazato M, Kimura K, Yoshino H, Inomata Y, Soper R T

机构信息

Department of Surgery, University of Iowa College of Medicine, Iowa City 52242, USA.

出版信息

Dig Dis Sci. 1996 Jul;41(7):1310-2. doi: 10.1007/BF02088552.

DOI:10.1007/BF02088552
PMID:8689904
Abstract

This report describes a technique to implant bipolar electrodes into the rat bowel. We implanted a total of 129 pairs of bipolar electrodes into the bowel of rats. 124 pairs of electrodes (96.3%) have continuously functioned allowing repeated myoelectrical readings. Of these, 69 electrodes functioned over 8 weeks. Only 5 electrodes (3.7%) failed. The advantage of our technique includes: (1) high success rate in implantation, (2) long term durability, and (3) less technical difficulty.

摘要

本报告描述了一种将双极电极植入大鼠肠道的技术。我们总共将129对双极电极植入大鼠肠道。124对电极(96.3%)持续发挥功能,可进行重复的肌电读数。其中,69根电极在8周以上发挥功能。只有5根电极(3.7%)出现故障。我们这项技术的优点包括:(1)植入成功率高,(2)长期耐用性,以及(3)技术难度较低。

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1
Bipolar electrode implantation for myoelectrical recordings of rat bowel.用于大鼠肠道肌电记录的双极电极植入
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本文引用的文献

1
CHRONIC ELECTRICAL ACTIVITY OF GASTRODUODENAL AREA: EFFECTS OF FOOD AND CERTAIN CATECHOLAMINES.胃十二指肠区域的慢性电活动:食物和某些儿茶酚胺的影响。
Am J Physiol. 1963 Sep;205:439-45. doi: 10.1152/ajplegacy.1963.205.3.439.
2
Motility of isolated bowel segment Iowa model III.离体肠段运动的爱荷华模型III。
Dig Dis Sci. 1994 Dec;39(12):2619-23. doi: 10.1007/BF02087699.
3
Effect of morphine sulfate on intestinal transit and myoelectric activity of the small intestine of the rat.硫酸吗啡对大鼠小肠肠推进及小肠肌电活动的影响。
J Pharmacol Exp Ther. 1980 Aug;214(2):333-8.
4
A method for long-term recording of intestinal mechanical and electrical activity in the unrestrained rat.
J Pharmacol Methods. 1981 Nov;6(3):233-42. doi: 10.1016/0160-5402(81)90112-1.
5
The isolated bowel segment (Iowa model II) created in functioning bowel.在有功能的肠管中创建的孤立肠段(爱荷华模型II)。
J Pediatr Surg. 1991 Jul;26(7):780-3. doi: 10.1016/0022-3468(91)90137-i.
6
The isolated bowel segment (Iowa model II): motility across the anastomosis with or without mesenteric division.孤立肠段(爱荷华模型II):有或无肠系膜分离情况下吻合口处的蠕动
J Pediatr Surg. 1992 Jun;27(6):691-5. doi: 10.1016/s0022-3468(05)80092-2.
7
Diaphragmatic and oesophageal activity in regurgitation in sheep: an electromyographic study.绵羊反流时的膈肌和食管活动:一项肌电图研究。
J Physiol. 1979 Jul;292:381-90. doi: 10.1113/jphysiol.1979.sp012858.