Rumeau-Rouquette C
Unité de Recherches Epidémiologiques sur la Santé des Femmes et des Enfants, INSERM U-149, Paris.
J Gynecol Obstet Biol Reprod (Paris). 1996;25(2):119-23.
Despite improvement in perinatal care, the prevalence of cerebral palsy has not decreased in France, Sweden, the United Kingdom or Australia. Based on a review of recent publications, the course of cerebral palsy can be partially explained by the increase in risk among very low birthweight and very pre-term infants whose survival is now better. Until recently, many publications have supported the hypothesis that asphyxia at birth was the major cause of cerebral palsy. However, these results have been widely questioned; the role of asphyxia remained unclear. In 1993 and 1994, several publications showed that there is a significant relationship between asphyxia and cerebral palsy, but that the role of asphyxia was overestimated in the past. The role of maternal and antenatal risk factors must also be taken into account. The prevention of cerebral palsy must be undertaken very early in pregnancy.
尽管围产期护理有所改善,但在法国、瑞典、英国或澳大利亚,脑瘫的患病率并未下降。根据对近期出版物的综述,脑瘫的病程可以部分归因于极低出生体重和极早产儿风险的增加,而这些婴儿现在的存活率更高。直到最近,许多出版物都支持出生时窒息是脑瘫主要原因的假说。然而,这些结果受到了广泛质疑;窒息的作用仍不明确。1993年和1994年,几份出版物表明窒息与脑瘫之间存在显著关系,但过去对窒息的作用估计过高。还必须考虑母亲和产前风险因素。脑瘫的预防必须在孕期很早就开始。