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脑瘫病因中产前因素及产科护理的影响。

Antenatal antecedents and the impact of obstetric care in the etiology of cerebral palsy.

作者信息

Clark Shannon M, Ghulmiyyah Labib M, Hankins Gary D V

机构信息

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, The University of Texas Medical Branch, Galveston, Texas 77555-0587, USA.

出版信息

Clin Obstet Gynecol. 2008 Dec;51(4):775-86. doi: 10.1097/GRF.0b013e3181870994.

DOI:10.1097/GRF.0b013e3181870994
PMID:18981802
Abstract

Cerebral palsy (CP) affects 2/1000 live-born children. Multiple antenatal factors, including preterm delivery, low birth weight, infection/inflammation, multiple gestation, and other pregnancy complications, are mostly associated with CP in both the preterm and term infant, with birth asphyxia playing a minor role. Owing to the increasing survival of the very preterm and very low birth weight infant secondary to improvements in neonatal and obstetric care, the incidence of CP may be increasing. The focus of this paper is to explore antenatal antecedents as etiologies of CP and the impact of obstetric care on the prevention of CP.

摘要

脑瘫(CP)影响千分之二的活产儿。多种产前因素,包括早产、低出生体重、感染/炎症、多胎妊娠和其他妊娠并发症,在早产和足月婴儿中大多与脑瘫相关,出生窒息起的作用较小。由于新生儿和产科护理的改善,极早产儿和极低出生体重儿的存活率增加,脑瘫的发病率可能正在上升。本文的重点是探讨作为脑瘫病因的产前因素以及产科护理对预防脑瘫的影响。

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