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大豆苷元和染料木黄酮在肠道细菌作用下的代谢

Metabolism of daidzein and genistein by intestinal bacteria.

作者信息

Chang Y C, Nair M G

机构信息

Department of Horticulture and Pesticide Research Center, Michigan State University, East Lansing 48824, USA.

出版信息

J Nat Prod. 1995 Dec;58(12):1892-6. doi: 10.1021/np50126a014.

DOI:10.1021/np50126a014
PMID:8691209
Abstract

The isoflavones daidzein [1] and genistein [2] were fermented with human fecal bacteria under anaerobic conditions. Dihydrodaidzein [3], benzopyran-4,7-diol,3-(4-hydroxyphenyl) [4], and equol [5] were isolated from the fermentation broth of 1. Only one metabolite, dihydrogenistein [6], was isolated and characterized from the fermentation broth of 2. Metabolites 3-6 were identified by spectral methods.

摘要

异黄酮黄豆苷元[1]和染料木黄酮[2]在厌氧条件下与人粪便细菌一起发酵。从1的发酵液中分离出二氢黄豆苷元[3]、苯并吡喃-4,7-二醇、3-(4-羟基苯基)[4]和雌马酚[5]。从2的发酵液中仅分离出一种代谢产物二氢染料木黄酮[6]并对其进行了表征。代谢产物3-6通过光谱方法鉴定。

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