霍奇金病全淋巴结照射所致的长期闭经。
Prolonged amenorrhea associated with total nodal irradiation for Hodgkin's disease.
作者信息
Halyard M Y, Cornella J L, Grado G L, Rizzo N R
机构信息
Department of Radiation Oncology, Mayo Clinic Scottsdale, Arizona 85259, USA.
出版信息
J Natl Med Assoc. 1996 Jun;88(6):391-3.
Pelvic irradiation in the treatment of Hodgkin's disease, including total nodal irradiation, may result in substantial radiation to the ovaries unless oophoropexy and central pelvic shielding is used. Despite such precautions, temporary or permanent amenorrhea may result due to direct or scattered radiation. This article describes a 32-year-old patient who underwent oophoropexy followed by total nodal irradiation for Hodgkin's disease. The patient became amenorrheic for 14 consecutive months. Spontaneous recovery of ovarian function with resumption of menses then occurred and has remained normal to date. The occurrence of prolonged but temporary amenorrhea should be recognized after pelvic radiotherapy for the treatment of Hodgkin's disease.
在治疗霍奇金淋巴瘤时进行盆腔照射，包括全淋巴结照射，若不采用卵巢固定术和盆腔中央屏蔽，可能会对卵巢造成大量辐射。尽管采取了这些预防措施，但直接或散射辐射仍可能导致暂时或永久性闭经。本文描述了一名32岁的患者，该患者因霍奇金淋巴瘤接受了卵巢固定术，随后进行了全淋巴结照射。患者连续闭经14个月。随后卵巢功能自发恢复，月经复潮，至今月经一直正常。在因治疗霍奇金淋巴瘤而进行盆腔放疗后，应认识到可能会出现长时间但暂时的闭经情况。
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