Baster T J, Gibbs J M, Richardson T
Anaesth Intensive Care. 1977 May;5(2):128-33. doi: 10.1177/0310057X7700500205.
Buprenorphine is a potent synthetic opioid-partial antagonist analgesic drug currently under clinical trial. When administered intravenously to human volunteers buprenorphine produced a significant depression of the ventilatory response to carbon dioxide stimulus for a period in excess of six hours.
丁丙诺啡是一种强效合成阿片类部分激动剂镇痛药,目前正处于临床试验阶段。当对人类志愿者静脉注射丁丙诺啡时,其对二氧化碳刺激的通气反应会出现超过6小时的显著抑制。