Orwin J M
Acta Anaesthesiol Belg. 1977;28(2):93-106.
Doxapram administered as a single injection or infusion satisfactorily counteracted the respiratory depression produced by buprenorphrine when administered one hour after the analgesic in healthy subjects. The respiratory stimulant effect was relatively short lived, however, a more prolonged effect was found by study of the displacement of the carbon dioxide response curve.
在健康受试者中，在使用丁丙诺啡镇痛一小时后给予多沙普仑单次注射或输注，能令人满意地对抗丁丙诺啡产生的呼吸抑制。然而，呼吸兴奋作用持续时间相对较短，通过研究二氧化碳反应曲线的位移发现了更持久的作用。
