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[红细胞碳水化合物代谢指标在慢性亚临床HBsAg携带状态中的诊断意义]

[Diagnostic significance of erythrocyte carbohydrate metabolism indicators in chronic subclinical HBsAG carrier state].

作者信息

Levina L D, Bezuglova I A, Proĭdakov M A

出版信息

Klin Med (Mosk). 1995;73(6):26-8.

PMID:8691773
Abstract

Erythrocytic activity of H-6-PDG and alpha-HPDG was studied in 32 chronic carriers of HBsAg free of any clinical or biochemical signs of viral hepatitis B. Puncture biopsy of the liver discovered chronic persistent hepatitis (CPH) in 25 patients. 7 cases had no changes of hepatic tissue. In these patients alpha-HPDG activity remained normal while in all the HBsAg carriers with latent CPH it was very high. For H-6-PDG, the activity was enhanced in 28 and 72% of HBsAg carriers, respectively. The above biochemical tests may serve markers of latent liver involvement in subclinical HBsAg carriers.

摘要

在32名无任何临床或生化乙肝病毒感染迹象的HBsAg慢性携带者中,研究了H-6-PDG和α-HPDG的红细胞活性。肝脏穿刺活检发现25例患者患有慢性持续性肝炎(CPH)。7例患者肝组织无变化。在这些患者中,α-HPDG活性保持正常,而在所有潜伏性CPH的HBsAg携带者中,其活性非常高。对于H-6-PDG,在HBsAg携带者中,其活性分别增强了28%和72%。上述生化检测可作为亚临床HBsAg携带者潜在肝脏受累的标志物。

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