Menicagli V
Arch Sci Med (Torino). 1982 Jan-Mar;139(1):99-104.
20 asymptomatic carriers of HBsAg antigen have been subjected to haemato-chemical examinations and liver biopsy and followed up after two years. The only altered serological test result regarded transaminases, except for one case where other liver function indices were irregular, and these were up in 13 cases at the first control and in 6 at the second. The histological changes observed in respectively 18 and 17 patients were in the majority of cases of persistent chronic hepatitis type. In one case the histopathological picture was related to active chronic hepatitis. It is therefore concluded that the term asymptomatic carrier is often inexact as the subjects are suffering from clinically silent chronic hepatitis.
对20名无症状乙肝表面抗原携带者进行了血液化学检查、肝活检，并随访了两年。唯一发生改变的血清学检测结果是转氨酶，只有一例其他肝功能指标异常，其中13例在首次检查时转氨酶升高，6例在第二次检查时升高。分别在18名和17名患者中观察到的组织学变化在大多数情况下为持续性慢性肝炎类型。在一例中，组织病理学表现与活动性慢性肝炎有关。因此得出结论，“无症状携带者”这一术语往往不准确，因为这些受试者患有临床无症状的慢性肝炎。
