儿童恶性骨肿瘤
Malignant bone tumors of childhood.
作者信息
Himelstein B P, Dormans J P
机构信息
Division of Oncology, Children's Hospital of Philadelphia, Pennsylvania, USA.
出版信息
Pediatr Clin North Am. 1996 Aug;43(4):967-84. doi: 10.1016/s0031-3955(05)70445-4.
PMID:8692590
Abstract
Improvements in diagnosis and treatment have increased survival for many children with malignant bone tumors. New molecular genetic discoveries are providing insights into the mechanisms of tumorigenesis and may provide novel therapeutic modalities based on interfering with aberrant transcriptional activation by hybrid transcripts.
摘要
诊断和治疗方面的进步提高了许多患有恶性骨肿瘤儿童的生存率。新的分子遗传学发现为肿瘤发生机制提供了见解，并可能基于干扰杂种转录本异常转录激活提供新的治疗方式。
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